Antioxidant and antiviral activity of common polyphenols against influenza A virus

Main Article Content

Antioxidant and antiviral activity of common polyphenols against influenza A virus

Tác giả

Tran Van Cuong
Nguyen Thi Thoa

Tóm tắt

Herein, we compared the antioxidant activity, cytotoxicity, and antiviral activity of ten common phenolic acids and flavonoids which were naturally occurred in many plants and by-products sources. Antioxidant activity was analyzed using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azinobis (3 ethylbenzothiazoline-6-sulfonic acids) (ABTS) radical-scavenging activity, while cytotoxicity and antiviral effects of the polyphenols were evaluated using MDCK cells line model. The results showed that different phenolic acids and flavonoids showed a significant difference in antioxidant activities as well as cytotoxicity. Amongst compounds tested, pyrogallol and catechin showed higher DPPH radical scavenging ability, while ellagic acid and quercetin were the higher ability for ABTS assay.  Furthermore, our results indicated that the antiviral activity potential varied significantly among polyphenols, that several compounds including gallic acid, quercetin, rutin and vanillic acid were a remarkable inhibited viral infection.

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Chuyên mục
Khoa học Tự nhiên
Tiểu sử của Tác giả

Tran Van Cuong

Faculty of Agriculture and Forestry, Tay Nguyen University;
Corresponding author: Tran Van Cuong; Tel: 0336984747; Email:

Nguyen Thi Thoa

Western Highlands Agriculture & Forestry Science Institute (WASI), Buon Ma Thuot, Dak Lak

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